Development and Validation of RP-HPLC Method for the Simultaneous Determination of Rabeprazole Sodium and Itopride Hydrochloride in Solid Dosage Form
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چکیده
منابع مشابه
Development and validation of RP-HPLC method for determination of content uniformity of rabeprazole sodium in its tablets dosage form
The aim of the present work was to develop simple, shorter and effective HPLC method with UV detection (285nm) and subsequent validation for the content uniformity determination of Rabeprazole Sodium in marketed tablet samples. The method uses isocratic mobile phase of 0.1M sodium phosphate buffer (pH adjusted to 6.5 with sodium hydroxide solution) and acetonitrile 65:35 compositions on reverse...
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A simple, sensitive and precise stability indicating HPLC method has been developed for the estimation of rabeprazole and itopride in combined dosage form. A Phenomenex Gemini C-18, 5 μm column with a mobile phase containing 0.02 M ammonium acetate (pH 6): acetonitrile: methanol (45: 20: 35, v/v/v) was used. The flow rate was 1.0 mL min and effluents were monitored at 284 nm. Rabeprazole and it...
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A simple, precise, sensitive, rapid and reproducible HPTLC method for the simultaneous estimation of the rabeprazole and itopride hydrochloride in tablets was developed and validated. This method involves separation of the components by TLC on precoated silica gel G60F254 plate with solvent system of n-butanol, toluene and ammonia (8.5:0.5:1 v/v/v) and detection was carried out densitometricall...
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The present study describes a simple, accurate, precise and cost effective UV-Vis Spectroscopic and RP-HPLC method for the estimation of Ibandronate sodium (IBN). The determination of Ibandronate sodium (IBN) was performed by both UV and RP-HPLC method using 215 nm as the determination wavelength. The drug was dissolved in NaOH solution (0.1N NaOH) for estimation in UV and in distilled water fo...
متن کاملA Rp-hplc Method for Determination of Diclofenac with Rabeprazole in Solid Dosage Form
To develop and validate simple, reproducible, stability indicating reverse phase high performance liquid chromatography for the simultaneous determination of Rebeprazole and Diclofenac in pharmaceutical solid dosage form. The method was based on HPLC separation of both drugs in reverse phase mode using Phenomenox C18 column with Waters HPLC system by using mobile phase composition of acetonitri...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2010
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2010/878624